PERCEPTIONS OF COGNITIVE TRAINING GAMES AND ASSESSMENT TECHNOLOGIES FOR DEMENTIA: ACCEPTABILITY STUDY WITH PATIENT AND PUBLIC INVOLVEMENT WORKSHOPS

Perceptions of Cognitive Training Games and Assessment Technologies for Dementia: Acceptability Study With Patient and Public Involvement Workshops

BackgroundCognitive training and assessment technologies offer the promise of dementia risk reduction and a more timely diagnosis of dementia, respectively.Cognitive training games may help reduce the lifetime risk of dementia by helping to build cognitive reserve, whereas cognitive assessment technologies offer the opportunity for a more convenien

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Recruitment of BAG2 to DNAJ-PKAc scaffolds promotes cell survival and resistance to drug-induced apoptosis in fibrolamellar carcinoma

Summary: The DNAJ-PKAc fusion kinase is a defining feature of fibrolamellar carcinoma (FLC).FLC tumors are notoriously resistant to standard chemotherapies, with aberrant kinase activity assumed to be a contributing factor.By combining proximity proteomics, biochemical analyses, and live-cell photoactivation microscopy, we demonstrate that DNAJ-PKA

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